Handbook

T

Tirzepatide

Tirzepatide is a once-weekly injectable medication used to treat type 2 diabetes, chronic weight management, and moderate to severe obstructive sleep apnea (OSA) in adults with obesity

It is a dual agonist for glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, making it unique compared to semaglutide, which is a GLP-1 receptor agonist only

Mechanism of Action

Mimics GIP and GLP-1 hormones, which stimulate insulin release after meals, reduce glucagon levels, slow gastric emptying, and suppress appetite

Increases insulin sensitivity and reduces food intake, aiding in blood sugar control and weight loss

Its dual action provides greater efficacy in glycemic control and weight reduction compared to GLP-1-only drugs like semaglutide

Research application

Copied from the handbook as research notes. and not instructions.

  • 10mg vial of Tirzepatide
  • Reconstitution volume: 2mL of BAC water
  • 2.5mg = 50 units
  • 5mg = 100 units
  • 7.5mg = 150 units
  • 10mg = 200 units
  • 12mg = 250 units
  • 15mg = 300 units
  • Weeks 1-4: 2.5mg
  • Weeks 5-8: 5mg
  • Weeks 9-12: 7.5mg
  • Weeks 13-16: 10mg (if further increase is needed)
  • Weeks 17-20: 12.5mg (if further increase is needed)
  • Weeks 21+: 15mg once weekly(maximum maintenance dose)

Unless other wise noted intermuscular (IM) peptides are commonly administered via subcutaneous (SQ) injection with 30-31 gauge syringes

From @BowTiedYukon

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The information provided is for educational and informational purposes only and is not medical advice. Always consult with your physician or a qualified healthcare provider before starting any health protocol or using any peptides

YOU assume full responsibility for YOUR actions and decisions. Do YOUR own research and make informed choices in consultation with a licensed medical professional

This guide is an independent work created by the author. It is not affiliated with, endorsed by, or associated with any company or organization

All peptides discussed are intended for research use only. They are not intended for human or animal consumption or for use in any diagnostic or therapeutic purposes

Unless other wise noted intermuscular (IM) peptides are commonly administered via subcutaneous (SQ) injection with 30-31 gauge syringes

This app is an alphabetical reader for BowTiedYukon’s free Peptide Handbook. It is not affiliated with Elite Research USA. His profile lists the code YUKON10.