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Tesofensine
Elite ResearchTesofensine is a triple monoamine reuptake inhibitor that blocks the reabsorption of serotonin, norepinephrine, and dopamine in the brain, increasing their levels
Originally developed by for Alzheimer’s and Parkinson’s diseases, it was found ineffective for these conditions but showed significant weight loss in clinical trials
It primarily works as an appetite suppressant and may increase resting energy expenditure
Research application
Copied from the handbook as research notes. and not instructions.
- 250 mcg daily: Often the starting dose, effective for weight loss
- 500 mcg daily: The most studied dose, yielding significant weight loss (up to 10% body weight over 6 months)
- 1000 mcg daily: Higher dose, used cautiously due to increased risk of side effects like elevated heart rate and blood pressure
Unless other wise noted intermuscular (IM) peptides are commonly administered via subcutaneous (SQ) injection with 30-31 gauge syringes
From @BowTiedYukon